Institute of Cancer Research: World’s largest sarcoma research database aims to revolutionise sarcoma treatment after multi-million pound investment

Institute of Cancer Research: World’s largest sarcoma research database aims to revolutionise sarcoma treatment after multi-million pound investment. “Researchers at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust, working alongside collaborators from around the globe, are set to begin work on the world’s largest digital hub of sarcoma clinical and research data after receiving a £2.5m grant.”

MSU Today: New Website Stimulates New Cancer Research Synergies At MSU

MSU Today: New Website Stimulates New Cancer Research Synergies At MSU. “Michigan State University has unveiled a new website highlighting the vast amount of cancer research being conducted throughout the university. The site…features the research of 95 faculty members spread across 20 departments and eight colleges.”

EurekAlert: ORNL researchers develop ‘multitasking’ AI tool to extract cancer data in record time

EurekAlert: ORNL researchers develop ‘multitasking’ AI tool to extract cancer data in record time. “To better leverage cancer data for research, scientists at [Oak Ridge National Laboratory] are developing an artificial intelligence-based natural language processing tool to improve information extraction from textual pathology reports. The project is part of a DOE-National Cancer Institute collaboration known as the Joint Design of Advanced Computing Solutions for Cancer (JDACS4C) that is accelerating research by merging cancer data with advanced data analysis and high-performance computing.”

Medical University of South Carolina: AI tool studied as way to provide cancer risk assessment in low-resource communities

Medical University of South Carolina: AI tool studied as way to provide cancer risk assessment in low-resource communities. “Originally designed as a type of social network provided through an app, ItRunsInMyFamily has evolved into a simple informatics tool that uses artificial intelligence and social networking to collect family health history from patients. Participants complete a short 10-minute questionnaire easily accessible through a website. The free survey, which was built by cancer and informatics experts, using the most current health care guidelines and models, helps individuals do a comprehensive hereditary risk assessment.”

EurekAlert: New open-source software judges accuracy of computer predictions of cancer genetics

EurekAlert: New open-source software judges accuracy of computer predictions of cancer genetics. “Because simple clinical methods to test for genetic variation are vulnerable to missing a lot of cell-to-cell variability, recent computer tools have been developed to predict and characterise genetic diversity within clinical tumour samples. However, there is no existing common benchmarking approach to determine the most accurate computational methods. The study, published in Nature Biotechnology, developed open-source software that can be used to judge the accuracy of computer predictions and establish this benchmark.”

Weill Cornell Medicine: Scientists Build the First Global Database and Roadmap for CAR Therapy Clinical Trials

Weill Cornell Medicine: Scientists Build the First Global Database and Roadmap for CAR Therapy Clinical Trials. “Weill Cornell Medicine scientists have built the first global database of clinical trials testing a rapidly expanding approach to cancer treatment that involves genetically modifying immune cells to recognize specific targets on a patient’s cancer cells and attack them. By analyzing the approach, called chimeric antigen receptor (CAR) therapies, the scientists designed a ‘therapeutic roadmap’ that identifies all current therapies as well as additional cancers that can be treated with them.”

Washington University School of Medicine in St. Louis: $3.7 million supports crowdsourced database of cancer genomics

Washington University School of Medicine in St. Louis: $3.7 million supports crowdsourced database of cancer genomics. “The database’s name is CIViC, which stands for Clinical Interpretations of Variants in Cancer. According to its founders, it is the only entirely open-source online resource for querying tumor mutations — like a Wikipedia for cancer genomics. Comparing CIViC to Wikipedia — an online encyclopedia maintained by volunteers — the Griffiths, who are twin brothers, designed a system that allows anyone to create an account and contribute information to the database. Experts in the field serve as editors, curating data that is incorporated into the system. It is also free for anyone to use.”

Pharmaphorum: IQVIA launches UK cancer database amid survival rate concern

Pharmaphorum: IQVIA launches UK cancer database amid survival rate concern. “As figures show the UK continues to lag behind other developed countries in cancer survival, a new project aims to create a national database with ambitious goals to challenge the variation in care standards in the NHS and encourage clinical trial research.”

The Hindu: ‘India-specific cancer genome database being developed’

The Hindu: ‘India-specific cancer genome database being developed’. “The Union Health Ministry, in collaboration with the Indian Institute of Technology-Madras, is developing India-specific cancer genome database that will help identify biomarkers specific to the Indian population. This will help in early diagnosis, and also identify drug targets for the Indian population.”

Science: In departure for NIH, Cancer Moonshot requires grantees to make papers immediately free

Science: In departure for NIH, Cancer Moonshot requires grantees to make papers immediately free. “The long-standing debate over open access to research results has been marked by a geographic divide. In Europe, some public funders have launched a high-profile open-access initiative, dubbed Plan S, that would ultimately require grantees to publish only in journals that immediately make papers free to all. But in the United States, federal agencies have stuck to a decade-old policy that allows grantees to publish in journals that keep papers behind a paywall for up to 1 year. Now, the divide is starting to blur, with one prominent U.S. research program starting to require immediate open access to the peer-reviewed publications it funds.”

Cancer. gov: Researchers create record-sized, integrated cellular cancer database

Cancer .gov: Researchers create record-sized, integrated cellular cancer database. “An international team of researchers have created a powerful new database that consolidates data on a record number of cancer drugs and cell lines. The freely available tool, called CellMinerCDB, can be used to explore connections between drugs and various features of cancer, such as genetic mutations, cell signatures, DNA methylation and more.”

New York Times: Top Cancer Researcher Fails to Disclose Corporate Financial Ties in Major Research Journals

New York Times: Top Cancer Researcher Fails to Disclose Corporate Financial Ties in Major Research Journals. “One of the world’s top breast cancer doctors failed to disclose millions of dollars in payments from drug and health care companies in recent years, omitting his financial ties from dozens of research articles in prestigious publications like The New England Journal of Medicine and The Lancet.”

New Atlas: Virtual Biobank revolutionizes to access human cancer tissues

New Atlas: Virtual Biobank revolutionizes to access human cancer tissues. “In a move that could revolutionize the development of new cancer treatments, researchers from the University of Newcastle and the Hunter Medical Research Institute (HMRI) have created the world’s first virtual platform to host 3D copies of human cancer tissues.”