Phys .org: New tool for understanding cells in health and disease

Phys .org: New tool for understanding cells in health and disease . “The freely accessible platform, which includes software and several gold standard datasets compares the performance of thousands of different single-cell analysis options, enabling researchers to identify the best method for the questions they wish to answer.”

BioSpace: New Tool Allows View of Cell Division in 3D Models

BioSpace: New Tool Allows View of Cell Division in 3D Models. “The Integrated Mitotic Stem Cell merges images of 15 separate cellular components, creating a 3-dimensional map of what a human cell looks like during different steps in cell division. The idea is that it can assist researchers in better understanding how the separate stages and different components of the cell work together—it’s also visually beautiful and entertaining, which makes it a valuable educational tool.”

UPI: Scientists use artificial intelligence to create cell database

UPI: Scientists use artificial intelligence to create cell database. “A new artificial intelligence could help sort normal cells from diseased cells, researchers report in a new study. The Human Cell Atlas is a deep learning algorithm method that uses single-cell RNA sequencing to distinguish activated and deactivated cells within humans at any point, according to a study published Wednesday in Nature Communications. The ability to pinpoint healthy cells from diseased cells at a given time within a person’s life cycle.”

Cancer. gov: Researchers create record-sized, integrated cellular cancer database

Cancer .gov: Researchers create record-sized, integrated cellular cancer database. “An international team of researchers have created a powerful new database that consolidates data on a record number of cancer drugs and cell lines. The freely available tool, called CellMinerCDB, can be used to explore connections between drugs and various features of cancer, such as genetic mutations, cell signatures, DNA methylation and more.”

DICE: Immune cell atlas goes live (EurekAlert)

EurekAlert: DICE: Immune cell atlas goes live . “Compare any two people’s DNA and you will find millions of points where their genetic codes differ. Now, scientists at La Jolla Institute for Immunology (LJI) are sharing a trove of data that will be critical for deciphering how this natural genetic variation shapes the immune system’s ability to protect our health.”

Allen Institute for Brain Science: Allen Institute for Brain Science Database Release Nearly Doubles Mouse Brain Cell Data

Allen Institute for Brain Science: Allen Institute for Brain Science Database Release Nearly Doubles Mouse Brain Cell Data. “The Allen Institute for Brain Science today announced the release of new data, tools to analyze those data and a new web-based 3D viewer to explore anatomy and connections in the mouse brain, the Allen Brain Explorer. Today’s data release almost doubles the number of mouse cells in the Allen Cell Types Database – raising the number included from just over 1,000 to slightly more than 1,900 cells – as well as adding new neuronal connectivity information to the Allen Mouse Brain Connectivity Atlas and adding more single-cell transcriptomics data from mouse, human and macaque brain cells.”

GeekWire: Biologists use artificial intelligence to flesh out 3-D views of a cell’s inner workings

GeekWire: Biologists use artificial intelligence to flesh out 3-D views of a cell’s inner workings. “What happens when you cross cell biology with artificial intelligence? At the Allen Institute for Cell Science, the answer isn’t super-brainy microbes, but new computer models that can turn simple black-and-white pictures of live human cells into color-coded, 3-D visualizations filled with detail. The online database, known as the Allen Integrated Cell, is now being made publicly available — and its creators say it could open up new windows into the workings of our cells.”