PubMed: Accuracy of Google Translate in translating the directions and counseling points for top-selling drugs from English to Arabic, Chinese, and Spanish

PubMed: Accuracy of Google Translate in translating the directions and counseling points for top-selling drugs from English to Arabic, Chinese, and Spanish. “For the top 100 drugs, 38 unique directions for use and 170 unique counseling points were identified for translation. For the 38 directions for use, 29 (76.3%) of the Arabic translations were accurate, 34 (89.5%) of the Chinese (simplified) translations were accurate, and 27 (71%) of the Spanish translations were accurate. For the 170 counseling points, 92 (54.1%) of the Arabic translations were accurate, 130 (76.5%) of the Chinese (simplified) translations were accurate, and 65 (38.2%) of the Spanish translations were accurate. Of the 247 inaccurate translations, 72 (29.1%) were classified as highly clinically significant or potentially life-threatening.”

University of Maine: Governor’s Office of Innovation, UMaine, DHHS launch Maine Drug Data Hub

University of Maine: Governor’s Office of Innovation, UMaine, DHHS launch Maine Drug Data Hub . “Maine Drug Data Hub links to data, reports and other dashboards related to drug problems and related Maine policies. It integrates data from public health, public safety, corrections and the judicial system using the 2021 Maine Opioid Response Strategic Plan as a framework. It also provides special ‘use-case’ portals for ease of use by policymakers, media and clinicians.”

EurekAlert: Personalised medications possible with 3D printing

EurekAlert: Personalised medications possible with 3D printing. “Customised medicines could one day be manufactured to patients’ individual needs, with University of East Anglia (UEA) researchers investigating technology to 3D ‘print’ pills. The team, including Dr Andy Gleadall and Prof Richard Bibb at Loughborough University, identified a new additive manufacturing method to allow the 3D printing of medicine in highly porous structures, which can be used to regulate the rate of drug release from the medicine to the body when taken orally.”

University of California San Francisco: UCSF and Johns Hopkins University Launch Digital Trove of Opioid Industry Documents

University of California San Francisco: UCSF and Johns Hopkins University Launch Digital Trove of Opioid Industry Documents. “UC San Francisco and Johns Hopkins University today announced the launch of the Opioid Industry Documents Archive, a digital repository of publicly disclosed documents from recent judgments, settlements, and ongoing lawsuits concerning the opioid crisis. The documents come from government litigation against pharmaceutical companies, including opioid manufacturers and distributors related to their contributions to the deadly epidemic, as well as litigation taking place in federal court on behalf of thousands of cities and counties in the United States.”

Mint: Pfizer begins human trials of new pill to treat coronavirus

Mint: Pfizer begins human trials of new pill to treat coronavirus. “If it succeeds in trials, the pill could be prescribed early in an infection to block viral replication before patients get very sick. The drug binds to an enzyme called a protease to keep the virus from replicating. Protease-inhibiting medicines have been successful in treating other types of viruses, include HIV and Hepatitis C.”

Festivals: ‘Grave concerns’ over drug safety this summer (BBC)

BBC: Festivals: ‘Grave concerns’ over drug safety this summer. “If lockdown is lifted as planned, large events are expected to go ahead from 21 June onwards in England – with Scotland, Wales and Northern Ireland aiming for a similar timescale. Charities are worried ‘pent-up’ energy could increase the amount people take. They’re also concerned about the strength of the drugs and the lack of testing to identify bad batches.”

EurekAlert: Leprosy drug holds promise as at-home treatment for COVID-19

EurekAlert: Leprosy drug holds promise as at-home treatment for COVID-19. “A Nature study authored by scientists at Sanford Burnham Prebys Medical Discovery Institute and the University of Hong Kong shows that the leprosy drug clofazimine, which is FDA approved and on the World Health Organization’s List of Essential Medicines, exhibits potent antiviral activities against SARS-CoV-2 and prevents the exaggerated inflammatory response associated with severe COVID-19. Based on these findings, a Phase 2 study evaluating clofazimine as an at-home treatment for COVID-19 could begin immediately.”

Inverse: A Surprising Treatment For Covid-19 Could Be The Key To Stopping Variants

Inverse: A Surprising Treatment For Covid-19 Could Be The Key To Stopping Variants. “Over 90 percent of France’s 88,933 deaths in the past year occurred in people ages 65 and older. And yet, at the psychiatric hospital filled with antidepressant-taking patients, many of whom were in that high-risk age group, only one died. A genuinely shocking contrast when you compare it with any other facilities with older adults. The antidepressants, evidence suggests, were helping these patients survive.”

New York Times: How the Search for Covid-19 Treatments Faltered While Vaccines Sped Ahead

New York Times: How the Search for Covid-19 Treatments Faltered While Vaccines Sped Ahead. “The government poured $18.5 billion into vaccines, a strategy that resulted in at least five effective products at record-shattering speed. But its investment in drugs was far smaller, about $8.2 billion, most of which went to just a few candidates, such as monoclonal antibodies. Studies of other drugs were poorly organized. The result was that many promising drugs that could stop the disease early, called antivirals, were neglected. Their trials have stalled, either because researchers couldn’t find enough funding or enough patients to participate.”

Penn State News: Facebook posts could identify substance use risk in homeless youth

Penn State News: Facebook posts could identify substance use risk in homeless youth. “In their work, researchers built novel detection systems, using machine learning and natural language processing techniques, that can identify certain kinds of substance use based on an individual’s Facebook posts. They focused their efforts on predicting substance use among homeless youth — a high-risk population with elevated rates of hard drug use.”

The Frontier: Oklahoma trying to return its $2m stockpile of hydroxychloroquine

The Frontier: Oklahoma trying to return its $2m stockpile of hydroxychloroquine. “In April, Gov. Kevin Stitt, who ordered the hydroxychloroquine purchase, defended it by saying that while it may not be a useful treatment for the coronavirus, the drug had multiple other uses and ‘that money will not have gone to waste in any respect.’ But nearly a year later the state is trying to offload the drug back to its original supplier, California-based FFF Enterprises, Inc, a private pharmaceutical wholesaler.”

San Francisco Chronicle: ‘New weapon’ to kill COVID? UCSF-led team finds drug that could be far more effective than remdesivir

San Francisco Chronicle: ‘New weapon’ to kill COVID? UCSF-led team finds drug that could be far more effective than remdesivir. “After a yearlong search for existing drugs that might help COVID-19 patients and point to a cure, a UCSF-led science team has identified what they say is an especially promising candidate: an anti-cancer drug that kills the coronavirus in lab studies and is almost 30 times more potent than remdesivir, one of the few antiviral drugs available to treat the disease.”

Vice: Darknet Drug Dealers Are Now Selling ‘Pfizer COVID Vaccines’

Vice: Darknet Drug Dealers Are Now Selling ‘Pfizer COVID Vaccines’. “At least two vendors that VICE World News spoke to over Wickr claimed to be pharmacists, insisting that they acquired the vaccine through the government and had already sold it to multiple customers. One claimed to have a stockpile of some 560 doses. When asked for proof of their qualifications and photographic evidence of the product, both refused. Later, one of them sent a high-quality stock image of a vial labelled ‘Coronavirus Vaccine’.”