University of Connecticut: Researchers to Expand the Encyclopedia of RNA

University of Connecticut: Researchers to Expand the Encyclopedia of RNA. “The National Human Genome Research Institute has awarded genomics expert Brent Graveley and his team $5.6-million to continue to work on an enormous encyclopedia of human RNA molecules and the proteins that bind to them. The grant is jointly awarded to Graveley and Gene Yeo of the University of California, San Diego.”

Tohoku University: A New Database Visualizing Fish Biodiversity Opens to the Public

Tohoku University: A New Database Visualizing Fish Biodiversity Opens to the Public. “Tohoku University professor Michio Kondoh has spearheaded the launch of ANEMONE DB – a new public database of fish biodiversity based on environmental DNA (eDNA)…. Unlike traditional biological surveys, where fish must be collected to be observed, eDNA surveys are straightforward, inexpensive and can detect rare or nearly extinct species. A simple sample of water taken from rivers, seas or oceans picks up DNA left behind by organisms and reveals crucial information, like population sizes and distribution.”

EurekAlert: Researchers reconstruct the genome of centuries-old E. coli using fragments extracted from an Italian mummy

EurekAlert: Researchers reconstruct the genome of centuries-old E. coli using fragments extracted from an Italian mummy. “An international team led by researchers at McMaster University, working in collaboration with the University of Paris Cité, has identified and reconstructed the first ancient genome of E. coli, using fragments extracted from the gallstone of a 16th century mummy.”

MIT News: New CRISPR-based map ties every human gene to its function

MIT News: New CRISPR-based map ties every human gene to its function. “The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including MIT’s Whitehead Institute for Biomedical Research, and was finally completed in 2003. Now, over two decades later, MIT Professor Jonathan Weissman and colleagues have gone beyond the sequence to present the first comprehensive functional map of genes that are expressed in human cells.”

France24: Scientists produce chimp genetic map to combat trafficking

France24: Scientists produce chimp genetic map to combat trafficking. “Scientists have produced the first genetic map of chimpanzees in the wild, offering a detailed reconstruction of the endangered species’ past migrations, and a new tool to combat illegal trafficking. The genomic catalogue, which includes 828 individuals from across their vast African range, can now be used to link kidnapped chimpanzees — or their meat and body parts — to their place of origin within 100 kilometers.”

Associated Press: Scientists finally finish decoding entire human genome

Associated Press: Scientists finally finish decoding entire human genome. “An international team described the first-ever sequencing of a complete human genome – the set of instructions to build and sustain a human being – in research published Thursday in the journal Science. The previous effort, celebrated across the world, was incomplete because DNA sequencing technologies of the day weren’t able to read certain parts of it. Even after updates, it was missing about 8% of the genome.”

UVA Health: A New Tool to Make Genomic Research Reflect the World’s Diversity

UVA Health: A New Tool to Make Genomic Research Reflect the World’s Diversity. “The new tool will allow researchers to compare natural variations in our genes against genome sequences collected from a diverse group of people. Until now, scientists have compared these variations with a ‘reference genome’ primarily sequenced from a few volunteers (~70% from one person) living near laboratories involved in the Human Genome Project almost 20 years ago. This represented genomes from a small number of people in a small number of countries.”

De-extinction puzzle: how decoding numbat DNA could help resurrect the Tasmanian tiger (The Guardian)

The Guardian: De-extinction puzzle: how decoding numbat DNA could help resurrect the Tasmanian tiger. “Researchers at DNA Zoo Australia have mapped the genome of the numbat for the first time. The milestone is notable in its own right, motivated by a desire to improve conservation efforts for the endangered termite-eating marsupial, which is now found only in small pockets of Western Australia. But in announcing the development last week, scientists also had a more extraordinary suggestion: that the numbat’s DNA could be used as a blueprint to bring its extinct cousin, the thylacine, back from the dead.”

University of Nebraska-Lincoln: Husker researcher building database to help farmers breed hardier sheep

University of Nebraska-Lincoln: Husker researcher building database to help farmers breed hardier sheep. “The project, funded by a $650,000 grant from the U.S. Department of Agriculture’s National Institute of Food and Agriculture, will develop a database of traits for robustness and climatic resilience. Researchers will assemble current and additional genetic data, as well as performance records, for several major U.S. sheep breeds: Katahdin, Polypay, Rambouillet and Suffolk.”

Augusta University: Small group of genetic variants found in extremely ill patients with COVID may help explain big differences in how sick people get

Augusta University: Small group of genetic variants found in extremely ill patients with COVID may help explain big differences in how sick people get. “The search to better understand the tremendous range of responses to infection with the COVID-19 virus — from symptom free to critically ill — has uncovered in some of the sickest patients a handful of rare structural gene variants involved in body processes, like inflammation, which the virus needs to be successful.”