EurekAlert: Altimmune COVID-19 vaccine candidate tested at UAB shows positive preclinical results

EurekAlert: Altimmune COVID-19 vaccine candidate tested at UAB shows positive preclinical results. “Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.”

Gulf Business: UAE to begin Covid-19 vaccine trials with 15,000 volunteers

Gulf Business: UAE to begin Covid-19 vaccine trials with 15,000 volunteers. “The UAE government has confirmed that it is set to begin Covid-19 vaccine trials in 15,000 volunteers imminently. The trials have been approved by the Ethics Committee Scientific research in Abu Dhabi, Dr. Abdul Rahman bin Mohammad bin Nasser Al Owais, Minister of Health and Prevention (MoHAP) said on Monday. Al Owais said that this Phase III stage includes testing two possible vaccines and added that the best scientific standards will be adopted when conducting the trials.”

The Guardian: Immunity to Covid-19 could be lost in months, UK study suggests

The Guardian: Immunity to Covid-19 could be lost in months, UK study suggests. “People who have recovered from Covid-19 may lose their immunity to the disease within months, according to research suggesting the virus could reinfect people year after year, like common colds. In the first longitudinal study of its kind, scientists analysed the immune response of more than 90 patients and healthcare workers at Guy’s and St Thomas’ NHS foundation trust and found levels of antibodies that can destroy the virus peaked about three weeks after the onset of symptoms then swiftly declined.”

Coronavirus warning from Italy: Effects of COVID-19 could be worse than first thought (Sky News)

Sky News: Coronavirus warning from Italy: Effects of COVID-19 could be worse than first thought. “The long-term effects of COVID-19, even on people who suffered a mild infection, could be far worse than was originally anticipated, according to researchers and doctors in northern Italy. Psychosis, insomnia, kidney disease, spinal infections, strokes, chronic tiredness and mobility issues are being identified in former coronavirus patients in Lombardy, the worst-affected region in the country.”

CNET: Give IBM your unused computing power to help cure coronavirus and cancer

CNET: Give IBM your unused computing power to help cure coronavirus and cancer. “When Sawyer Thompson was just 12 years old, he discovered his father Brett unconscious in their Washington, DC area home. Sawyer called an ambulance and Brett was rushed to the hospital, where the family learned the worst: He had brain cancer. After a year of surgeries, radiation and chemotherapy, Brett’s cancer is in remission. But Sawyer wanted to do more to fight against cancer, and is tapping his interest in tech to make a bigger difference.”

Pharmaceutical Technology: Altimmune partners with DynPort on intranasal Covid-19 vaccine

Pharmaceutical Technology: Altimmune partners with DynPort on intranasal Covid-19 vaccine. “Biopharmaceutical firm Altimmune has signed a teaming agreement with DynPort Vaccine to support US Government funding efforts for the development of its intranasal Covid-19 vaccine candidate, AdCOVID. If successful, the partnership will be extended to programme management, drug development and regulatory support for the vaccine product.”

CNN: How coronavirus affects the entire body

CNN: How coronavirus affects the entire body. “Coronavirus damages not only the lungs, but the kidneys, liver, heart, brain and nervous system, skin and gastrointestinal tract, doctors said Friday in a review of reports about Covid-19 patients. The team at the Columbia University Irving Medical Center in New York City — one of the hospitals flooded with patients in the spring — went through their own experiences and collected reports from other medical teams around the world.”

EurekAlert: Building surge ICU capacity during COVID-19

EurekAlert: Building surge ICU capacity during COVID-19. “To prepare for current and future waves of COVID-19, the U.S. Army’s Telemedicine and Advanced Technology Research Center asked teams from across the country to compete to build a telehealth prototype that would provide adequate ICU capacity when cases surge. Of the 78 teams that competed, only nine were invited to complete a series of tasks designed to establish the feasibility of their prototypes. A Medical University of South Carolina team of bioinformatics, telehealth and critical care experts was one of those nine.”

Washington Post: The retired inventor of N95 masks is back at work, mostly for free, to fight covid-19

Washington Post: The retired inventor of N95 masks is back at work, mostly for free, to fight covid-19. “Peter Tsai retired two years ago, but the materials scientist says he’s never been busier. When the novel coronavirus began gripping the globe in March, Tsai was summoned from his short-lived retirement. He was in urgent demand because he is the inventor who, in 1995, patented the filtration material used in disposable N95 respirators. The coveted masks are in short supply and are desperately needed by health-care workers and others who require protection from the highly contagious coronavirus.”

CNN: Here’s how to volunteer for a Covid-19 vaccine trial

CNN: Here’s how to volunteer for a Covid-19 vaccine trial. “Wednesday, a new website… went live allowing people in the United States to register to take part in clinical trials for vaccines. The website will handle registration for the four large vaccine studies that are expected to start this summer and fall, and any others that follow.”

CNN: Operation Warp Speed commits $1.6 billion to Covid-19 vaccine maker Novavax

CNN: Operation Warp Speed commits $1.6 billion to Covid-19 vaccine maker Novavax. “‘Operation Warp Speed,’ the federal government’s Covid-19 vaccine program, on Tuesday announced the largest government Covid-19 vaccine contract to date — a $1.6 billion contract with Novavax, a Maryland biotech company.”

Plus: Study: Lower COVID Risk for HIV-Positive People on Antiretrovirals

Plus: Study: Lower COVID Risk for HIV-Positive People on Antiretrovirals. “A study of tens of thousands of HIV-positive Spaniards found they faced less risk of dying or getting seriously ill from COVID-19 than people without HIV. Researchers specifically cited the use of antiretroviral therapy — specifically medications that include a nucleotide reverse transcriptase inhibitor (NRTI) backbone of tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) — as a factor in the lower risks, according to the study published in the Annals of Internal Medicine and reported in the American Journal of Managed Care.”

ProPublica: Agonizing Lag in Coronavirus Research Puts Pregnant Women and Babies at Risk

ProPublica: Agonizing Lag in Coronavirus Research Puts Pregnant Women and Babies at Risk. “The CDC had been asserting that pregnant women don’t seem to be at higher risk for severe complications from the virus. As recently as late May, a spokesperson told ProPublica, ‘Current evidence shows pregnant women have the same risk of severe illness from COVID-19 as adults who are not pregnant.’ Then, the agency abruptly changed its tone. In its first examination of U.S. data on COVID-19 in pregnancy, the CDC found that expectant mothers with the virus had a 50% higher chance of being admitted to intensive care and a 70% higher chance of being intubated than nonpregnant women in their childbearing years.”

Coronavirus autopsies: A story of 38 brains, 87 lungs and 42 hearts (Washington Post)

Washington Post: Coronavirus autopsies: A story of 38 brains, 87 lungs and 42 hearts. “When pathologist Amy Rapkiewicz began the grim process of opening up the coronavirus dead to learn how their bodies went awry, she found damage to the lungs, kidneys and liver consistent with what doctors had reported for months. But something was off.”

New York Times: DNA Linked to Covid-19 Was Inherited From Neanderthals, Study Finds

New York Times: DNA Linked to Covid-19 Was Inherited From Neanderthals, Study Finds. “A stretch of DNA linked to Covid-19 was passed down from Neanderthals 60,000 years ago, according to a new study. Scientists don’t yet know why this particular segment increases the risk of severe illness from the coronavirus. But the new findings, which were posted online on Friday and have not yet been published in a scientific journal, show how some clues to modern health stem from ancient history.”