COVID-19: Online tool identifies patients at highest risk of deterioration (MedicalXpress)

MedicalXpress: COVID-19: Online tool identifies patients at highest risk of deterioration. “A new risk-stratification tool which can accurately predict the likelihood of deterioration in adults hospitalised with COVID-19 has been developed by researchers from the UK Coronavirus Clinical Characterisation Consortium (known as ISARIC4C). Researchers say the online tool, made freely available to NHS doctors from today, could support clinicians’ decision making—helping to improve patient outcomes and ultimately save lives.”

New York Times: Trump and Friends Got Coronavirus Care Many Others Couldn’t

New York Times: Trump and Friends Got Coronavirus Care Many Others Couldn’t. “Ben Carson, Chris Christie and Donald J. Trump are not the sturdiest candidates to conquer the coronavirus: older, in some cases overweight, male and not particularly fit. Yet all seem to have gotten through Covid-19, and all have gotten an antibody treatment in such short supply that some hospitals and states are doling it out by lottery. Now Rudolph W. Giuliani, the latest member of President Trump’s inner circle to contract Covid-19, has acknowledged that he received at least two of the same drugs the president received. He even conceded that his ‘celebrity’ status had given him access to care that others did not have.”

NBC News: After first round of vaccine distributions, bulk of planning remains unfinished

NBC News: After first round of vaccine distributions, bulk of planning remains unfinished. “A panel of the Centers for Disease Control and Prevention this week announced its guidelines for the first phase of the most ambitious national vaccination campaign in modern history. Yet beyond the guidelines advising states about how to deploy their vaccines — and a large Defense Department operation to deliver them — the Trump administration hasn’t prepared for a major federal role, a lack of planning that is causing significant anxiety among state and local health officials.”

BBC: Trump lawyer Rudy Giuliani receiving same Covid drugs as president

BBC: Trump lawyer Rudy Giuliani receiving same Covid drugs as president. “President Donald Trump’s personal lawyer, Rudy Giuliani, has revealed in a call to his own radio show that he is being treated for coronavirus with the same drug cocktail his boss received when he was ill with Covid-19. He was admitted to hospital on Sunday after becoming the latest official close to Mr Trump to test positive.”

ScienceBlog: Doctors Use Existing Treatment Earlier To Save The Lives Of Covid-19 Patients

ScienceBlog: Doctors Use Existing Treatment Earlier To Save The Lives Of Covid-19 Patients. “The lives of patients hospitalised with COVID-19 are being saved by doctors who are using an existing medical treatment at an earlier stage. Dr Luigi Sedda of Lancaster University analysed the results from the team at Wrightington, Wigan and Leigh Teaching Hospitals NHS Trust (WWL). Their research has now been published in the prestigious medical journal BMJ Respiratory Open.”

Politico: Game-changing coronavirus medicine gears up for production

Politico: Game-changing coronavirus medicine gears up for production. “Amid alarming spikes in infections and a wave of new restrictions announced across Europe, some good news is emerging: Monoclonal antibodies are likely to be the first game-changing therapy against COVID-19. Big drugmakers have ample experience in manufacturing these kinds of medicines, and their existing facilities can readily be converted to produce doses of a future COVID-19 treatment, experts say.”

Washington Post: Trump politicizes promising coronavirus antibody treatments, erroneously calling them a ‘cure’

Washington Post: Trump politicizes promising coronavirus antibody treatments, erroneously calling them a ‘cure’. “Trump claimed on videos posted on Twitter Wednesday and Thursday that the drug he received, a cocktail of laboratory-made antibodies from Regeneron Pharmaceuticals, is a “cure” that would soon be broadly available — even as the company disclosed that in the next few months, it would have enough supply to treat only the number of Americans sickened in the last week, or about 300,000 doses. A similar antibody drug, made by Eli Lilly & Co., shows similar promise but will also be in short supply, with about 1 million doses by year’s end.”

STAT News: Trump is receiving dexamethasone, a steroid usually given to patients with severe Covid-19

STAT News: Trump is receiving dexamethasone, a steroid usually given to patients with severe Covid-19. “Dexamethasone is generally reserved for patients who have serious disease. The National Institutes of Health’s treatment guidelines for Covid-19 say dexamethasone should be used only in hospitalized patients who are on ventilators or who require supplemental oxygen, and specifically ‘recommends against using dexamethasone for the treatment of Covid-19 in patients who do not require supplemental oxygen.’”

Washington Post: These laboratory-made antibodies are a best bet for a coronavirus treatment, but there won’t be enough

Washington Post: These laboratory-made antibodies are a best bet for a coronavirus treatment, but there won’t be enough. “Predictions about coronavirus vaccines have become almost deafening in recent weeks, but whether or not the first doses of a vaccine arrive this year, some people will continue to get sick. A medication that could prevent people from progressing to the point that they need a hospital bed or ventilator could be a bridge to a vaccine, or it could be the lifeline that could give people confidence to return to normal life even once vaccines are developed.”

Covid 19 coronavirus: Hundreds of women desperate after endometriosis treatment cancelled (New Zealand Herald)

New Zealand Herald: Covid 19 coronavirus: Hundreds of women desperate after endometriosis treatment cancelled. “Endometriosis New Zealand chief executive Deborah Bush said that during the seven-week lockdown alone the organisation received cries for help from 568 women, far more than usual, with some suicidal because they were struggling to deal with their condition.”

BBC: Coronavirus and the cancelled kidney transplant

BBC: Coronavirus and the cancelled kidney transplant. “Lockdown has resulted in a dramatic change in the lives of many young people – and this is especially true for Mali Elwy. The 19-year-old student was due to receive a kidney transplant from her brother Morgan on 24 August, but the operation has had to be cancelled due to the coronavirus crisis.”

Purdue University: Augmented reality tool shown to help surgeons remotely guide first responders in battlefield-like scenarios

Purdue University: Augmented reality tool shown to help surgeons remotely guide first responders in battlefield-like scenarios. “A Purdue University-led study is the first to show medics successfully performing surgery in life-like simulations of these war zones by receiving guidance from surgeons through an augmented reality headset. The work is joint with Purdue’s School of Industrial Engineering and the Department of Computer Science.”

Columbia University: Neutralizing Antibodies Isolated from COVID-19 Patients May Suppress Virus

Columbia University: Neutralizing Antibodies Isolated from COVID-19 Patients May Suppress Virus. “Researchers at Columbia University Irving Medical Center have isolated antibodies from several COVID-19 patients that, to date, are among the most potent in neutralizing the SARS-CoV-2 virus. These antibodies could be produced in large quantities by pharmaceutical companies to treat patients, especially early in the course of infection, and to prevent infection, particularly in the elderly.”